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From Wikipedia, the free encyclopedia

Dennis Bray
Born (1939-06-28) 28 June 1939 (age 84)[1]
NationalityBritish
AwardsMicrosoft European Science Award (2007)
Scientific career
Fieldscomputational biology, microbiology, neurobiology
InstitutionsUniversity of Cambridge

Dennis Bray (born 1939)[2] is an active emeritus professor at University of Cambridge. His group is also part of the Oxford Centre for Integrative Systems Biology. After a first career in Neurobiology, working on cell growth and movement, Dennis Bray moved in Cambridge to develop computational models of cell signaling, in particular in relation to bacterial chemotaxis.

On 3 November 2006 he was awarded the Microsoft European Science Award for his work on chemotaxis of E. coli.[3][4]

YouTube Encyclopedic

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  • What is a gene?

Transcription

Stated Clearly presents What exactly is a gene? What exactly is a gene? each one of our cells contains 46 strands of DNA. A single strand is made up of millions of particles called nucleotides. Nucleotides come in 4 different types which scientists have labeled A C T and G A gene is a special stretch of DNA: a sequence of As Cs Ts and Gs, that codes for something. a gene contains information for a cell to read but what exactly does that information do? a gene contains information for a cell to read but what exactly does that information do? You might have heard that there's a blue eye gene, a freckle gene, and possibly even in anger gene, but single genes don't literally make things like eyeballs are freckles or temper tantrums. Genes make proteins. Genes make proteins. Those proteins then interact with each other and all sorts of other chemicals inside the body to build things like freckles, eye pigments, and mood altering hormones. A single strand of DNA contains thousands of genes or unique protein recipes. Humans have roughly twenty thousand all together. Some genes are small, only about three hundred letters long, others are well over a million. The length and sequence of a gene determine the size and shape of the protein it builds. The size and shape of the protein, determine the function that protein will have inside the body. Hemoglobin for example, is a protein structure found in red blood cells. Its unique shape and size allowed it to capture oxygen molecules when blood flows near the lungs, and then release them later when blood flows near oxygen starved tissues. Pepsin is a digestive protein. Its unique shape allows it to break down food inside your stomach so it can be absorbed by the body. Keratin is a structural protein its unique shape and size allow it to link together with other karatin proteins to form hard structures like fingernails, claws and beaks. Different creatures have different genes which is ultimately why their bodies look and function differently, but one of the many reasons scientists believe all life on earth is related is that the basic DNA code, the language of As Cs Ts and Gs, is pretty much the same for all living things. Many creatures even share some of the same genes. You may not be too surprised to learn that humans and chimps (which are closely related) You may not be too surprised to learn that humans and chimps (which are closely related) share about ninety six percent of their genetic code, but what would you think that a lowly fruit fly has in common with a beautiful swimsuit model? surprisingly, about half of its genes. about half of its genes. Because all creatures use DNA in pretty much the same way, genetic engineers have found that they can take the gene from say a bacteria cell, and inserted into the DNA of an animal or plant cell. That animal or plant cell will read the gene and produce the bacterial protein. Engineers have mixed and matched the genes or many different organisms to produce many new creatures, including corn that is toxic to insects but supposedly safe for human consumption, tomatoes that last up to twice as long and the grocery store before going bad, and a new form of bacteria that produces the human protein insulin, which we then collect from these bacteria and give to people with diabetes who need extra insulin to survive. So just to sum things up a bit, So just to sum things up a bit, What exactly is it gene? A gene is a special stretch of DNA, not an entire strand of DNA, justice a segment, that codes for something. Each gene is like a unique recipe which usually tells a cell how how to make a protein or a group of proteins. Different creatures have different genes, but all genes are written in the same basic DNA language of As Cs Ts and Gs of As Cs Ts and Gs of As Cs Ts and Gs I'm Jon Perry, and that's Genes, Stated Clearly.

Books

  • Wetware: A Computer in Every Living Cell (2009) ISBN 0-300-14173-4, ISBN 978-0-300-14173-3[5]
  • Essential Cell Biology (2003) (with Bruce Alberts, Karen Hopkin, Alexander Jonhson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter) ISBN 0-8153-3480-X, ISBN 978-0-8153-3480-4
  • Cell Movements: From Molecules to Motility (2000) ISBN 0-8153-3282-3, ISBN 978-0-8153-3282-4
  • Essential Cell Biology: An Introduction to the Molecular Biology of the Cell (1997) (with Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter) ISBN 0-8153-2971-7, ISBN 978-0-8153-2971-8
  • Molecular Biology of the Cell (3rd ed, 1994) (with Bruce Alberts, Julian Lewis, Martin Raff, Keith Roberts, James D. Watson) ISBN 0-8153-1927-4, ISBN 978-0-8153-1927-6
  • Cell Movements (1992) ISBN 0-8153-0717-9, ISBN 978-0-8153-0717-4
  • Molecular Biology of the Cell (2nd ed, 1989) (with Bruce Alberts, Keith Roberts, Julian Lewis, Martin Raff) ISBN 0-8240-3695-6, ISBN 978-0-8240-3695-9
  • Molecular Biology of the Cell (1st ed, 1982) (with Bruce Alberts, Keith Roberts, Julian Lewis, Martin Raff, James D Watson) ISBN 0-8240-7283-9, ISBN 978-0-8240-7283-4

Main scientific publications

  • Bray D (1970) Surface movements during growth of single explanted neurons. Proc Natl Acad Sci USA,
  • Bray D (1973) Model for Membrane Movements in the Neural Growth Cone. Nature, 244: 93 - 96
  • Bray D, White JG (1988) Cortical flow in animal cells. Science, 239: 883-888
  • Bray D (1990) Intracellular signalling as a parallel distributed process. Journal of Theoretical Biology, 143: 215-231
  • Bray D (1995) Protein molecules as computational elements in living cells. Nature, 376: 307-312
  • Bray D, Levin MD, Morton-Firth CJ (1998) Receptor clustering as a cellular mechanism to control sensitivity. Nature, 393: 85-88

Mention in Popular Science[vague]

Professor Franklin M. Harold writes "The theme [of a protein's shape and functionality being altered by interaction with its environment] comes with numerous variations, some of which are discussed in a thought-provoking article by Dennis Bray [author references Dr. Bray's 1995 article] that examines proteins as information-processing devices."[6]

References

  1. ^ "Bray, Dennis". Social Networks and Archival Content.
  2. ^ "Dennis Bray". King's College, London.
  3. ^ "Microsoft Research – Emerging Technology, Computer, and Software Research". research.microsoft.com. Retrieved 6 November 2006.
  4. ^ "Computer bug study wins top prize". news.bbc.co.uk. 3 November 2006. Retrieved 6 November 2006.
  5. ^ "Wetware: A Computer in Every Living Cell « Kurzweil".
  6. ^ Harold, Franklin M. (2001). The way of the cell: molecules, organisms, and the order of life. New York: Oxford University Press. pp. 76. ISBN 0-19-513512-1.

External links

This page was last edited on 16 February 2024, at 16:48
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